Objective: To study various gynecological problems in postmenopausal women; to study the awareness of gynecological problems in postmenopausal women. Materials and methods: It was a cross-sectional study carried out in the Department of Obstetrics and Gynecology, NKP Salve Institute of Medical Sciences & Research Center, Lata Mangeshkar Hospital, Nagpur, Maharashtra, India, from August 2015 to July 2016. The study population comprised all postmenopausal women attending the gynecological outpatient department and those admitted in the gynecological ward. The total number of postmenopausal women included in the study was 200. For the awareness of gynecological problems among postmenopausal women, a structured pretested questionnaire was used. Results: The mean age at menopause was 45 to 49 years. The most common gynecological problem was postmenopausal bleeding (45%), followed by pelvic organ prolapse (41.50%), frequent micturition (10%), white discharge (9%), burning micturition (8.50%), stress incontinence (4%), and lump in the abdomen (3.50%). Out of the total women of postmenopausal bleeding, 86% were benign and 14% were malignant. In our study, with the women with postmenopausal bleeding, cervical cancer was the most common malignancy (10%). Conclusion: The most common gynecological problem was postmenopausal bleeding (45%) followed by pelvic organ prolapse (41.50%). The commonest symptom of underlying malignancy was postmenopausal bleeding and the commonest malignancy in our study in the women with the symptom of postmenopausal bleeding was cervical cancer (10%).