Journal of SAFOMS

Register      Login

VOLUME 6 , ISSUE 2 ( July-December, 2018 ) > List of Articles


A Study on Relationship of Endometrial Thickness and Abnormal Uterine Bleeding in Perimenopausal Women

Jyoti Jaiswal, Anand Jaiswal

Keywords : AUB, Endometrial thickness, Perimenopause

Citation Information : Jaiswal J, Jaiswal A. A Study on Relationship of Endometrial Thickness and Abnormal Uterine Bleeding in Perimenopausal Women. J South Asian Feder Menopause Soc 2018; 6 (2):106-111.

DOI: 10.5005/jp-journals-10032-1150

License: CC BY-NC 4.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Aims and objectives: To study the possible relationship between abnormal uterine bleeding (AUB) and endometrial thickness in perimenopausal women. Materials and methods: A prospective observational study conducted on 60 cases of AUB in perimenopausal age (41–55 years) group. Results: Institutional incidence of AUB in general and AUB in perimenopausal age was 10.7% and 29.38% respectively. Maximum cases were para 3 and of age 41–45 years (78.33%). Cases presented with irregular and heavy menstrual bleeding (76.66%). About one-third (33.33%) of the study subjects were suffering from severe and life-threatening anemia due to AUB. 90% study subjects required a blood transfusion, maximum of them were transfused preoperatively. As per PALM-COEIN classification, maximum cases had leiomyoma (41.66%) as a structural cause of AUB followed by malignancy and hyperplasia (33.33%). Majority of cases (45%) presenting with AUB had an endometrial thickness between 6–9 mm. Mean endometrial thickness was maximum in cases of AUB M that is 10.33 mm followed by AUB-L 7.56 mm, and AUB-A 7.2 mm. Majority of cases (70%) with ET 9 mm or less were having mild to moderate blood loss. Majority of cases with severe blood loss higher endometrial thickness; half subjects had ET >10 mm, and few had ET 16 to 21 mm. Cafeteria approach for choosing the management line was given. Most of the perimenopausal cases preferred the surgical line of management (83.33%) over medical method (13.33%) despite counseling. Conclusion: Endometrial thickness of more than 7 mm remains a common feature with estrogen-dependent conditions like fibroid, adenomyosis, hyperplasia, and malignancy even during perimenopause. Clinical Significance: AUB in perimenopause needs vigilant surveillance, and endometrial thickness may be a relevant tool for it.

PDF Share
  1. Pillai SS. Sonographic and histopathological correlation and evaluation of endometrium in perimenopausal women with abnormal uterine bleeding. Int J Reprod Contracept Obst Gynecol. 2014 Mar;3(1):113-117.
  2. Najeeb R, Awan AS, et al. Role of transvaginal sonography in assessment of abnormal uterine bleeding in perimenopausal age group. J Ayub Med Coll Abbottabad 2010;22(1):87-90.
  3. Sajitha K. Study of histopathological pattern of endometrium in abnormal uterine bleeding CHRISMED. J Health Res 2001; 1(2):76-81.
  4. Shobhitha GL, Kumari VI, et al. Endometrial study by TVS and It's correlation with histopathology in abnormal uterine bleeding. J Dental Med Sci 2015;14(4):21-32
  5. Parveen N, Majeed R, et al. Attitude and knowledge of medical students of Isra University about dysmenorrhoea and its treatment. J Ayub Med Coll Abbottabad 2009;21:159-162.
  6. Breitkopf DM, Frederickson RA, et al. Detection of benign endometrial masses by endometrial stripe measurement in premenopausal women. Obstet Gynecol 2004;104(1):120-125
  7. Muzaffar M, Akhtar K A, et al. Menstrual Irregularities with excessive blood logs: A clinicopathological correlation. J Pak Med Assoc 2005; 55: 486-489
  8. Thakur S., Nayak SR, et al. Geriatric problem: Abnormal uterine bleeding per vaginum after the age of 40. J Obetetr Gynaecol India 1976;44(3):580-586.
  9. Talukdar B, Mahela S. Abnormal uterine bleeding in perimenopausal women: Correlation with sonographic findings and histopathological examination of hysterectomy specimens. J Midlife Health 2016;7(2):73-77.
  10. Katke RD, Zarariya AN. Use of diagnostic hysteroscopy in abnormal uterine bleeding in perimenopausal age group and its clinicopathological co-relation with ultrasound and histopathology findings: experience in a tertiary care institute. Int J Reprod Contracept Obstet Gynecol 2015;4(2):413-418.
  11. Dasgupta S, Chakraborty B, et al. Abnormal uterine bleeding in perimenopausal age: Diagnostic options and Accuracy. J Obstet Gynecol India 2011;61(2):189-194.
  12. Pinion SB, Parkin DE, et al. Randomised trial of hysterectomy, endometrial laser ablation, and transcervical endometrial resection for dysfunctional uterine bleeding. BMJ 1994;309:979-983.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.