Patients diagnosed with cancer have a lifetime risk of developing another de novo malignancy. The incidence of two primaries in the same patient is an extremely rare condition, and there are no specific guidelines for management. There are less than ten reported cases of coincidental renal cell cancer in a patient with endometrial cancer. In a woman who presented with postmenopausal bleeding with endometrial carcinoma, an incidental primary renal cell carcinoma was diagnosed and treated successfully by a multidisciplinary team of gynecologists, oncosurgeon, urologist, radiologist, pathologist, and a medical oncologist. We are reporting this case due to its rarity and clinical interest. A high index of clinical suspicion would go a long way in the management of such tumors.
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