Background: Hysteroscopy has been proved to have diagnostic accuracy in abnormal uterine bleeding (AUB) and helps in localizing the lesions with minimal errors. However, histopathology has been considered as the gold standard in evaluating the pathological causes of AUB. The reliability of hysteroscopy as a single procedure to manage AUB has not been explored so far. This study was carried out to evaluate the validity of hysteroscopy in the diagnosis of AUB. Materials and methods: This cross-sectional study was carried out among 50 patients diagnosed with AUB. Hysteroscopy was performed along with curettage and the tissue obtained was sent for histopathological examination. All the participants underwent diagnostic hysteroscopy and hysteroscopic-guided curettage. The hyseroscopic findings were correlated with histopathological findings. Results: We observed that hysteroscopy was an effective diagnostic tool for detecting endometrial hyperplasia, with a specificity of 93% and negative predictive value of 90.1%. As far as polyps were concerned, we observed that hysteroscopy was an effective screening and diagnostic tool of detecting polyps, with a sensitivity of 93.3% and specificity of 82.8%. Conclusion: Because the histopathological findings significantly correlated with the hysteroscopy findings, we are of the opinion that hysteroscopy may as well replace the traditional dilatation and curettage and at the same time replace invasive procedures for endometrial sampling.